Read e-book online ADME-Enabling Technologies in Drug Design and Development PDF

By Donglu Zhang,Sekhar Surapaneni

ISBN-10: 0470542780

ISBN-13: 9780470542781

A entire advisor to state of the art instruments in ADME research

The final decade has visible large growth within the improvement of analytical ideas equivalent to mass spectrometry and molecular biology instruments, leading to very important advances in drug discovery, really within the quarter of absorption, distribution, metabolism, and excretion (ADME).

ADME-Enabling applied sciences in Drug layout and improvement specializes in the present cutting-edge within the box, providing a accomplished overview of the newest instruments for producing ADME information in drug discovery. It examines the broadest attainable variety of accessible applied sciences, giving readers the knowledge they should decide upon the fitting instrument for a given program, a key needful for acquiring favorable leads to a well timed model for regulatory filings. With over thirty contributed chapters by means of a world crew of specialists, the ebook provides:

  • A thorough exam of present instruments, protecting either electronic/mechanical applied sciences and biologically established ones

  • Coverage of purposes for every expertise, together with key parameters, optimum stipulations for meant effects, protocols, and case studies

  • Detailed dialogue of rising instruments and strategies, from stem cells and genetically converted animal versions to imaging technologies

  • Numerous figures and diagrams during the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical technological know-how will locate ADME-Enabling applied sciences in Drug layout and improvement a useful consultant to the whole drug improvement strategy, from discovery to regulatory issues.

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ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni

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