By Randy Read,Alexandre G. Urzhumtsev,Vladimir Y. Lunin
This work provides a photograph of the state-of-the-art of recent biomolecular crystallography, from crystallisation via constitution choice or even interactive presentation at the web. tools riding the newest automatic constitution decision pipelines are defined, in addition to how you can take care of difficulties equivalent to crystal pathologies that also call for specialist analysis. those tools are illustrated via their software to difficulties of serious organic curiosity, corresponding to the molecular equipment underlying the supplement pathway, the mechanism of motion of monoamine oxidase inhibitors, and the constitution of the eukaryotic ribosome. Complementary methods, comparable to neutron diffraction, small attitude X-ray scattering, coherent diffraction and computational modelling, also are explored.
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Advancing Methods for Biomolecular Crystallography (NATO Science for Peace and Security Series A: Chemistry and Biology) by Randy Read,Alexandre G. Urzhumtsev,Vladimir Y. Lunin